| Gene Information | |
|---|---|
| Gene Name | RIC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1423 |
| Protein Names | Guanine nucleotide exchange factor subunit RIC1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog) (RAB6A-GEF complex partner protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000107036 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q4ADV7 |
| Gene Card | RIC1 |
| Uniprot ID | Q4ADV7 |
| Pfam | PF07064 |
| In ASD | no |
| Allosteric Prediction | no (-0.959387787) |
| Ortholog in Animals | Alpaca_ RIC1 ( ortholog_one2one ) Dog_ RIC1 ( ortholog_one2one ) GuineaPig_ RIC1 ( ortholog_one2one ) Macaque_ RIC1 ( ortholog_one2one ) Mouse_ Ric1 ( ortholog_one2one ) Pig_ RIC1 ( ortholog_one2one ) Rat_ Ric1 ( ortholog_one2one ) Rabbit_ RIC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Present in kidney and various cell lines (at protein level). Widely expressed at low level. {ECO:0000269|PubMed:10718198, ECO:0000269|PubMed:16112082}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:23091056}. Membrane {ECO:0000269|PubMed:23091056}. |
| Mouse PG classification | NA |
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