| Gene Information | |
|---|---|
| Gene Name | SLC6A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 617 |
| Protein Names | Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2) |
| Target Name | sodium-dependent noradrenaline transporter |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000103546 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P23975 |
| Gene Card | SLC6A2 |
| Uniprot ID | P23975 |
| Pfam | PF00209 |
| In ASD | yes |
| Allosteric Prediction | yes (1.140641487) |
| Ortholog in Animals | Alpaca_ SLC6A2 ( ortholog_one2one ) Dog_ SLC6A2 ( ortholog_one2one ) GuineaPig_ SLC6A2 ( ortholog_one2one ) Macaque_ SLC6A2 ( ortholog_one2one ) Mouse_ Slc6a2 ( ortholog_one2one ) Pig_ SLC6A2 ( ortholog_one2one ) Rat_ Slc6a2 ( ortholog_one2one ) Rabbit_ SLC6A2 ( ortholog_one2one ) |
| Ohnologs | SLC6A3 |
| Paralogs | SLC6A20, SLC6A9, SLC6A18, SLC6A7, SLC6A4, SLC6A16, SLC6A8, SLC6A5, SLC6A14, SLC6A6, SLC6A15, SLC6A13, SLC6A11, SLC6A19, SLC6A1, SLC6A17, SLC6A12, SLC6A3 |
| Tissue | adrenal.gland, placenta |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11568323 rs1805064 rs1805065 rs1805066 rs45564432 rs5563 rs5565 rs5566 rs5567 rs2234910 rs121918126 rs5570 rs1805067 rs5558 rs5559 rs3743788 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:11343649}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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