| Gene Information | |
|---|---|
| Gene Name | SLC6A18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 628 |
| Protein Names | Inactive sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164363 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96N87 |
| Gene Card | SLC6A18 |
| Uniprot ID | Q96N87 |
| Pfam | PF00209 |
| In ASD | no |
| Allosteric Prediction | no (-0.756033605) |
| Ortholog in Animals | Alpaca_ SLC6A18 ( ortholog_one2one ) Dog_ SLC6A18 ( ortholog_one2one ) GuineaPig_ SLC6A18 ( ortholog_one2one ) Macaque_ SLC6A18 ( ortholog_one2one ) Mouse_ Slc6a18 ( ortholog_one2one ) Pig_ SLC6A18 ( ortholog_one2one ) Rat_ Slc6a18 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC6A20, SLC6A9, SLC6A2, SLC6A7, SLC6A4, SLC6A16, SLC6A8, SLC6A5, SLC6A14, SLC6A6, SLC6A15, SLC6A13, SLC6A11, SLC6A19, SLC6A1, SLC6A17, SLC6A12, SLC6A3 |
| Tissue | kidney |
| Tissue Specificity | Abundantly expressed in kidney, but not in intestine. {ECO:0000269|PubMed:15286787}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34469326 rs7728667 rs7705355 rs113861454 rs4073918 rs147278493 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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