Gene Information
Gene NamePECI
OrganismHomo sapiens (Human)
Gene Length394
Protein NamesEnoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO75521
Gene CardECI2
Uniprot IDO75521
PfamPF00887; PF00378
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityAbundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells. {ECO:0000269|PubMed:10419495, ECO:0000269|PubMed:15217832}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001790(Rat);0.028571(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2CQU  (NMR  2F6Q  (X-ray  1.95A  4U18  (X-ray  2.64A  4U19  (X-ray  1.88A  4U1A  (X-ray  2.85A 
DBSNP rs3177253  rs7166 
Subcellular location [CC][Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:Q5XIC0}.;
[Isoform 2]: Peroxisome matrix {ECO:0000269|PubMed:10419495}.
Mouse PG classificationNA
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