| Gene Information | |
|---|---|
| Gene Name | SLC5A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 672 |
| Protein Names | Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2) |
| Target Name | sodium/glucose cotransporter 2 |
| Target Type | Successful target |
| Gene Age | 950 ( ENSG00000140675 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P31639 |
| Gene Card | SLC5A2 |
| Uniprot ID | P31639 |
| Pfam | PF00474 |
| In ASD | no |
| Allosteric Prediction | yes (0.842679176) |
| Ortholog in Animals | Alpaca_ SLC5A2 ( ortholog_one2one ) GuineaPig_ SLC5A2 ( ortholog_one2one ) Macaque_ SLC5A2 ( ortholog_one2one ) Mouse_ Slc5a2 ( ortholog_one2one ) Pig_ SLC5A2 ( ortholog_one2one ) Rat_ Slc5a2 ( ortholog_one2one ) Rabbit_ SLC5A2 ( ortholog_one2one ) |
| Ohnologs | SLC5A1, SLC5A4 |
| Paralogs | SLC5A11, SLC5A5, SLC5A8, SLC5A1, SLC5A6, SLC5A9, SLC5A3, SLC5A10, SLC5A4, SLC5A12, SLC5A7 |
| Tissue | kidney |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 7VSI (EM 2.95A ) |
| DBSNP | rs61742739 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:Q923I7}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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