| Gene Information | |
|---|---|
| Gene Name | LIMS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000072163 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7Z4I7 |
| Gene Card | LIMS2 |
| Uniprot ID | Q7Z4I7 |
| Pfam | PF00412 |
| In ASD | no |
| Allosteric Prediction | no (-1.479509414) |
| Ortholog in Animals | Alpaca_ LIMS2 ( ortholog_one2one ) Dog_ LIMS2 ( ortholog_one2one ) GuineaPig_ LIMS2 ( ortholog_one2one ) Macaque_ LIMS2 ( ortholog_one2one ) Mouse_ Lims2 ( ortholog_one2one ) Pig_ LIMS2 ( ortholog_one2one ) Rat_ Lims2 ( ortholog_one2one ) Rabbit_ LIMS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LIMS3, LIMS4, LIMS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3IXE (X-ray 1.90A ) |
| DBSNP | rs754385302 rs768056213 rs869025562 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. Cell junction, focal adhesion {ECO:0000269|PubMed:12167643}. Cell membrane {ECO:0000269|PubMed:12167643}; Peripheral membrane protein {ECO:0000269|PubMed:12167643}; Cytoplasmic side {ECO:0000269|PubMed:12167643}. |
| Mouse PG classification | NA |
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