| Gene Information | |
|---|---|
| Gene Name | SEC31B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1179 |
| Protein Names | Protein transport protein Sec31B (SEC31-like protein 2) (SEC31-related protein B) (SEC31B-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000075826 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NQW1 |
| Gene Card | SEC31B |
| Uniprot ID | Q9NQW1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.934994592) |
| Ortholog in Animals | Alpaca_ SEC31B ( ortholog_one2one ) Dog_ SEC31B ( ortholog_one2one ) GuineaPig_ SEC31B ( ortholog_one2one ) Macaque_ SEC31B ( ortholog_one2one ) Mouse_ Sec31b ( ortholog_one2one ) Pig_ SEC31B ( ortholog_one2one ) Rat_ Sec31b ( ortholog_one2one ) Rabbit_ SEC31B ( ortholog_one2one ) |
| Ohnologs | SEC31A |
| Paralogs | SEC31A |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level). {ECO:0000269|PubMed:10788476, ECO:0000269|PubMed:16495487}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002240(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3763695 rs7074707 rs3793706 rs2295774 rs2295772 rs2295771 rs11819496 rs17113157 rs2298075 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16495487}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:16495487}; Peripheral membrane protein {ECO:0000269|PubMed:16495487}; Cytoplasmic side {ECO:0000269|PubMed:16495487}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16495487}; Peripheral membrane protein {ECO:0000269|PubMed:16495487}. |
| Mouse PG classification | NA |
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