| Gene Information | |
|---|---|
| Gene Name | SH3PX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 595 |
| Protein Names | Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y5X1 |
| Gene Card | SNX9 |
| Uniprot ID | Q9Y5X1 |
| Pfam | PF10456; PF00787; PF00018 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:10531379}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2RAI (X-ray 3.20A ) 2RAJ (X-ray 2.45A ) 2RAK (X-ray 3.00A ) 3DYT (X-ray 2.08A ) 3DYU (X-ray 4.10A ) 3LGE (X-ray 2.20A ) 7OJ9 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network. Cell projection, ruffle. Cytoplasm. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation. Colocalizes with the actin cytoskeleton at the cell membrane. |
| Mouse PG classification | NA |
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