| Gene Information | |
|---|---|
| Gene Name | RGS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1198 |
| Protein Names | Regulator of G-protein signaling 3 (RGP3) (RGS3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000138835 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P49796 |
| Gene Card | RGS3 |
| Uniprot ID | P49796 |
| Pfam | PF00168; PF00595; PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-0.023693939) |
| Ortholog in Animals | Alpaca_ RGS3 ( ortholog_one2one ) Dog_ RGS3 ( ortholog_one2one ) GuineaPig_ RGS3 ( ortholog_one2one ) Macaque_ RGS3 ( ortholog_one2one ) Mouse_ Rgs3 ( ortholog_one2one ) Rat_ Rgs3 ( ortholog_one2one ) Rabbit_ RGS3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RGS18, RGS5, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2F5Y (X-ray 2.39A ) 2OJ4 (X-ray 2.30A ) 3FBK (X-ray 2.00A ) |
| DBSNP | rs16933949 rs41305473 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9858594}. Nucleus {ECO:0000269|PubMed:10749886}. Cell membrane {ECO:0000269|PubMed:9858594}; Peripheral membrane protein {ECO:0000269|PubMed:9858594}. Note=Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886). |
| Mouse PG classification | NA |
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