Gene Information
Gene NameSLC35D2
OrganismHomo sapiens (Human)
Gene Length337
Protein NamesUDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (Homolog of Fringe connection protein 1) (HFRC1) (SQV7-like protein) (SQV7L) (Solute carrier family 35 member D2) (UDP-galactose transporter-related protein 8) (UGTrel8)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000130958 )
Evolutionary StageEukaryota
AlphaFoldDBQ76EJ3
Gene CardSLC35D2
Uniprot IDQ76EJ3
PfamPF03151
In ASDno
Allosteric Predictionno (-1.241399548)
Ortholog in AnimalsAlpaca_ SLC35D2 ( ortholog_one2one )
Dog_ HSD17B3 ( ortholog_one2one )
GuineaPig_ SLC35D2 ( ortholog_one2one )
Macaque_ SLC35D2 ( ortholog_one2one )
Mouse_ Slc35d2 ( ortholog_one2one )
Pig_ SLC35D2 ( ortholog_one2one )
Rat_ Slc35d2 ( ortholog_one2one )
Rabbit_ SLC35D2 ( ortholog_one2one )
OhnologsSLC35D1
ParalogsSLC35C1, SLC35E4, SLC35C2, SLC35D3, SLC35D1, SLC35E3, SLC35E1, SLC35E2B, TMEM241
TissueNA
Tissue SpecificityHighly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus. {ECO:0000269|PubMed:15607426}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1051763 
Subcellular location [CC]Golgi apparatus membrane {ECO:0000269|PubMed:15082721, ECO:0000269|PubMed:15607426};
Multi-pass membrane protein {ECO:0000269|PubMed:15082721, ECO:0000269|PubMed:15607426}.
Mouse PG classificationNA
click here to return to the previous page