| Gene Information | |
|---|---|
| Gene Name | XPO7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1087 |
| Protein Names | Exportin-7 (Exp7) (Ran-binding protein 16) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000130227 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UIA9 |
| Gene Card | XPO7 |
| Uniprot ID | Q9UIA9 |
| Pfam | PF03810 |
| In ASD | no |
| Allosteric Prediction | no (-0.38933946) |
| Ortholog in Animals | Alpaca_ XPO7 ( ortholog_one2one ) Dog_ XPO7 ( ortholog_one2one ) GuineaPig_ XPO7 ( ortholog_one2one ) Macaque_ XPO7 ( ortholog_one2one ) Mouse_ Xpo7 ( ortholog_one2one ) Pig_ XPO7 ( ortholog_one2one ) Rat_ Xpo7 ( ortholog_one2one ) Rabbit_ XPO7 ( ortholog_one2one ) |
| Ohnologs | RANBP17 |
| Paralogs | RANBP17, XPO4 |
| Tissue | NA |
| Tissue Specificity | Strong expression in testis, thyroid and bone marrow, low expression in lung, liver and small intestine, no expression in thymus, and remaining tissues studied have moderate expression. Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:11071879, ECO:0000269|PubMed:22509282}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001445(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17856894 rs17856895 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11024021, ECO:0000269|PubMed:22509282}. Nucleus {ECO:0000269|PubMed:11024021}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:11024021}. |
| Mouse PG classification | NA |
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