| Gene Information | |
|---|---|
| Gene Name | SLC2A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver) (GLUT-2) |
| Target Name | solute carrier family 2, facilitated glucose transporter member 2 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000163581 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P11168 |
| Gene Card | SLC2A2 |
| Uniprot ID | P11168 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | yes (1.196500107) |
| Ortholog in Animals | Alpaca_ SLC2A2 ( ortholog_one2one ) Dog_ SLC2A2 ( ortholog_one2one ) GuineaPig_ SLC2A2 ( ortholog_one2one ) Macaque_ SLC2A2 ( ortholog_one2one ) Mouse_ Slc2a2 ( ortholog_one2one ) Pig_ SLC2A2 ( ortholog_one2one ) Rat_ Slc2a2 ( ortholog_one2one ) Rabbit_ SLC2A2 ( ortholog_one2one ) |
| Ohnologs | SLC2A4, SLC2A1 |
| Paralogs | SLC2A8, SLC2A7, SLC2A6, SLC2A5, SLC2A11, SLC2A1, SLC2A4, SLC2A3, SLC2A14, SLC2A13, SLC2A9, SLC2A12, SLC2A10 |
| Tissue | liver, kidney, small.intestine |
| Tissue Specificity | Liver, insulin-producing beta cell, small intestine and kidney. {ECO:0000269|PubMed:3399500, ECO:0000269|PubMed:8457197}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7637863 rs1800572 rs5400 rs121909741 rs121909747 rs2229608 rs121909744 rs28928874 rs5397 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28083649}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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