Gene Information
Gene NameSLC25A6
OrganismHomo sapiens (Human)
Gene Length298
Protein NamesADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Target Nameadp/atp translocase 3
Target TypeNA
Gene Age55 ( ENSG00000169100 )
Evolutionary StageEukaryota
AlphaFoldDBP12236
Gene CardSLC25A6
Uniprot IDP12236
PfamPF00153
In ASDno
Allosteric Predictionyes (0.941729258)
Ortholog in AnimalsAlpaca_ SLC25A6 ( ortholog_one2one )
Dog_ SLC25A6 ( ortholog_one2one )
Macaque_ SLC25A6 ( ortholog_one2one )
Pig_ SLC25A6 ( ortholog_one2one )
OhnologsSLC25A5, SLC25A4
ParalogsSLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A11, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A4, SLC25A40, SLC25A10, SLC25A18, SLC25A24, SLC25A44, SLC25A31, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A27, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A13, SLC25A33, SLC25A25, SLC25A26, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17
TissueNA
Tissue SpecificityExpressed in erythrocytes (at protein level). {ECO:0000269|PubMed:27641616}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Mitochondrion inner membrane {ECO:0000250|UniProtKB:P02722};
Multi-pass membrane protein {ECO:0000255}. Membrane {ECO:0000269|PubMed:27641616};
Multi-pass membrane protein {ECO:0000255}. Note=The complex formed with ARL2BP, ARL2 and SLC25A6/ANT3 is expressed in mitochondria (By similarity). May localize to non-mitochondrial membranes (By similarity). {ECO:0000250|UniProtKB:P12235}.
Mouse PG classificationNA
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