| Gene Information | |
|---|---|
| Gene Name | SLC25A4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 298 |
| Protein Names | ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4) |
| Target Name | adp/atp translocase 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000151729 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P12235 |
| Gene Card | SLC25A4 |
| Uniprot ID | P12235 |
| Pfam | PF00153 |
| In ASD | no |
| Allosteric Prediction | yes (0.475606893) |
| Ortholog in Animals | Alpaca_ SLC25A4 ( ortholog_one2one ) Dog_ SLC25A4 ( ortholog_one2one ) GuineaPig_ SLC25A4 ( ortholog_one2one ) Macaque_ SLC25A4 ( ortholog_one2one ) Mouse_ Slc25a4 ( ortholog_one2one ) Pig_ SLC25A4 ( ortholog_one2one ) Rat_ Slc25a4 ( ortholog_one2one ) |
| Ohnologs | SLC25A5, SLC25A6, SLC25A31 |
| Paralogs | SLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A11, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A40, SLC25A10, SLC25A18, SLC25A24, SLC25A44, SLC25A31, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A27, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A13, SLC25A33, SLC25A25, SLC25A26, SLC25A6, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17 |
| Tissue | NA |
| Tissue Specificity | Expressed in erythrocytes (at protein level). {ECO:0000269|PubMed:27641616}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs886041081 rs104893876 rs28999114 rs104893873 rs121912683 rs886041082 rs770816416 rs104893874 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:21586654}; Multi-pass membrane protein {ECO:0000255}. Membrane {ECO:0000269|PubMed:27641616}; Multi-pass membrane protein {ECO:0000255}. Note=The complex formed with ARL2BP, ARL2 and SLC25A4/ANT1 is expressed in mitochondria (By similarity). May localize to non-mitochondrial membranes (PubMed:27641616). {ECO:0000250|UniProtKB:P48962, ECO:0000269|PubMed:27641616}. |
| Mouse PG classification | NA |
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