| Gene Information | |
|---|---|
| Gene Name | SLITRK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 837 |
| Protein Names | SLIT and NTRK-like protein 4 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000179542 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IW52 |
| Gene Card | SLITRK4 |
| Uniprot ID | Q8IW52 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-1.505464765) |
| Ortholog in Animals | Alpaca_ SLITRK4 ( ortholog_one2one ) Dog_ SLITRK4 ( ortholog_one2one ) Macaque_ SLITRK4 ( ortholog_one2one ) Mouse_ Slitrk4 ( ortholog_one2one ) Pig_ SLITRK4 ( ortholog_one2one ) Rat_ Slitrk4 ( ortholog_one2one ) Rabbit_ SLITRK4 ( ortholog_one2one ) |
| Ohnologs | SLITRK3, SLITRK5, SLITRK1, SLITRK6 |
| Paralogs | TLR9, LRRC70, LRFN2, LRFN5, SLITRK3, LRFN4, GP5, SLITRK2, LINGO1, TPBGL, SLITRK6, LRFN1, LRRN1, SLITRK1, LRTM2, SLIT3, LRRN2, LRRN3, SLIT2, LRRC38, LINGO2, SLIT1, SLITRK5, LRRC55, LRFN3 |
| Tissue | adrenal.gland, brain |
| Tissue Specificity | Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors. {ECO:0000269|PubMed:14557068}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs143575705 rs781863874 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:27812321}. |
| Mouse PG classification | NA |
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