Gene Information
Gene NameSLC25A31
OrganismHomo sapiens (Human)
Gene Length315
Protein NamesADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000151475 )
Evolutionary StageEukaryota
AlphaFoldDBQ9H0C2
Gene CardSLC25A31
Uniprot IDQ9H0C2
PfamPF00153
In ASDno
Allosteric Predictionno (-0.338872775)
Ortholog in AnimalsAlpaca_ SLC25A31 ( ortholog_one2one )
Dog_ SLC25A31 ( ortholog_one2one )
GuineaPig_ SLC25A31 ( ortholog_one2one )
Macaque_ SLC25A31 ( ortholog_one2one )
Mouse_ Slc25a31 ( ortholog_one2one )
Pig_ SLC25A31 ( ortholog_one2one )
Rat_ Slc25a31 ( ortholog_one2one )
Rabbit_ SLC25A31 ( ortholog_one2one )
OhnologsSLC25A4
ParalogsSLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A11, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A4, SLC25A40, SLC25A10, SLC25A18, SLC25A24, SLC25A44, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A27, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A13, SLC25A33, SLC25A25, SLC25A26, SLC25A6, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17
Tissuetestis
Tissue SpecificityExpressed in brain, liver, sperm and testis (PubMed:15670820, PubMed:17137571). In testis, expressed at higher level in spermatocytes, while it is expressed at lower level in spermatogonial cells (PubMed:17681941). Expressed in erythrocytes (at protein level) (PubMed:27641616). {ECO:0000269|PubMed:15670820, ECO:0000269|PubMed:17137571, ECO:0000269|PubMed:17681941, ECO:0000269|PubMed:27641616}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Mitochondrion inner membrane {ECO:0000250|UniProtKB:P02722};
Multi-pass membrane protein {ECO:0000255}. Membrane {ECO:0000269|PubMed:27641616};
Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:17137571};
Multi-pass membrane protein {ECO:0000255}. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region (PubMed:17137571). May localize to non-mitochondrial membranes (PubMed:27641616). {ECO:0000269|PubMed:17137571, ECO:0000269|PubMed:27641616}.
Mouse PG classificationNA
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