| Gene Information | |
|---|---|
| Gene Name | SLC25A27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 323 |
| Protein Names | Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000153291 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95847 |
| Gene Card | SLC25A27 |
| Uniprot ID | O95847 |
| Pfam | PF00153 |
| In ASD | no |
| Allosteric Prediction | no (-0.631457885) |
| Ortholog in Animals | Alpaca_ SLC25A27 ( ortholog_one2one ) Dog_ SLC25A27 ( ortholog_one2one ) GuineaPig_ SLC25A27 ( ortholog_one2one ) Macaque_ SLC25A27 ( ortholog_one2one ) Mouse_ Slc25a27 ( ortholog_one2one ) Pig_ SLC25A27 ( ortholog_one2one ) Rat_ Slc25a27 ( ortholog_one2one ) Rabbit_ SLC25A27 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A11, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A4, SLC25A40, SLC25A10, SLC25A18, SLC25A24, SLC25A44, SLC25A31, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A13, SLC25A33, SLC25A25, SLC25A26, SLC25A6, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17 |
| Tissue | NA |
| Tissue Specificity | Found in adult and fetal brain. Present in most of the brain tissues, with low levels in spinal chord, corpus callosum and substantia nigra. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17853162 rs35884480 |
| Subcellular location [CC] | Mitochondrion inner membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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