Gene Information
Gene NameSLC25A13
OrganismHomo sapiens (Human)
Gene Length675
Protein NamesElectrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (Calcium-binding mitochondrial carrier protein Aralar2) (ARALAR-related gene 2) (ARALAR2) (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13)
Target Namecalcium-binding mitochondrial carrier protein aralar2
Target TypeNA
Gene Age1488 ( ENSG00000004864 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UJS0
Gene CardSLC25A13
Uniprot IDQ9UJS0
PfamPF00153
In ASDno
Allosteric Predictionyes (0.820529909)
Ortholog in AnimalsAlpaca_ SLC25A13 ( ortholog_one2one )
Dog_ SLC25A13 ( ortholog_one2one )
GuineaPig_ SLC25A13 ( ortholog_one2one )
Macaque_ SLC25A13 ( ortholog_one2one )
Mouse_ Slc25a13 ( ortholog_one2one )
Pig_ SLC25A13 ( ortholog_one2one )
Rat_ Slc25a13 ( ortholog_one2one )
Rabbit_ SLC25A13 ( ortholog_one2one )
OhnologsSLC25A12
ParalogsSLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A11, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A4, SLC25A40, SLC25A10, SLC25A18, SLC25A24, SLC25A44, SLC25A31, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A27, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A33, SLC25A25, SLC25A26, SLC25A6, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17
Tissuesubstantia.nigra
Tissue SpecificityHigh levels in liver and low levels in kidney, pancreas, placenta, heart and brain. {ECO:0000269|PubMed:10369257, ECO:0000269|PubMed:10642534}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4P5W  (X-ray  2.40A  ) 
DBSNP rs1131697  rs10255762  rs80338727 
Subcellular location [CC]Mitochondrion inner membrane {ECO:0000269|PubMed:10642534, ECO:0000269|PubMed:11566871};
Multi-pass membrane protein {ECO:0000269|PubMed:11566871}.
Mouse PG classificationHPG
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