| Gene Information | |
|---|---|
| Gene Name | SLC25A11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000108528 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q02978 |
| Gene Card | SLC25A11 |
| Uniprot ID | Q02978 |
| Pfam | PF00153 |
| In ASD | no |
| Allosteric Prediction | no (-0.377733135) |
| Ortholog in Animals | Alpaca_ SLC25A11 ( ortholog_one2one ) Dog_ SLC25A11 ( ortholog_one2one ) GuineaPig_ SLC25A11 ( ortholog_one2one ) Macaque_ SLC25A11 ( ortholog_one2one ) Mouse_ Slc25a11 ( ortholog_one2one ) Pig_ SLC25A11 ( ortholog_one2one ) Rat_ Slc25a11 ( ortholog_one2one ) Rabbit_ SLC25A11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC25A23, SLC25A35, SLC25A38, SLC25A12, SLC25A22, SLC25A29, UCP3, SLC25A21, SLC25A48, SLC25A42, SLC25A3, SLC25A28, UCP2, UCP1, SLC25A34, SLC25A15, SLC25A32, SLC25A53, SLC25A4, SLC25A40, SLC25A10, SLC25A18, SLC25A24, SLC25A44, SLC25A31, SLC25A5, SLC25A39, SLC25A36, SLC25A14, SLC25A27, SLC25A1, SLC25A41, SLC25A43, SLC25A47, SLC25A20, SLC25A37, SLC25A13, SLC25A33, SLC25A25, SLC25A26, SLC25A6, SLC25A45, SLC25A2, SLC25A51, SLC25A52, SLC25A30, SLC25A19, SLC25A16, SLC25A17 |
| Tissue | NA |
| Tissue Specificity | Most highly expressed in the heart. {ECO:0000269|PubMed:21448454}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.114286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1567651815 rs1203876038 rs1567650859 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P97700}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P97700}. |
| Mouse PG classification | NA |
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