| Gene Information | |
|---|---|
| Gene Name | SLC22A17 |
| Organism | Homo sapiens (Human) |
| Gene Length | 538 |
| Protein Names | Solute carrier family 22 member 17 (24p3 receptor) (24p3R) (Brain-type organic cation transporter) (Lipocalin-2 receptor) (Neutrophil gelatinase-associated lipocalin receptor) (NgalR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000092096 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WUG5 |
| Gene Card | SLC22A17 |
| Uniprot ID | Q8WUG5 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | no (-0.729294625) |
| Ortholog in Animals | Alpaca_ SLC22A17 ( ortholog_one2one ) Dog_ SLC22A17 ( ortholog_one2one ) GuineaPig_ SLC22A17 ( ortholog_one2one ) Macaque_ SLC22A17 ( ortholog_one2one ) Mouse_ Slc22a17 ( ortholog_one2one ) Pig_ SLC22A17 ( ortholog_one2one ) Rat_ Slc22a17 ( ortholog_one2one ) Rabbit_ SLC22A17 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC22A24, SLC22A12, SLC22A1, SLC22A6, SVOP, SLC22A7, SLC22A11, SLC22A23, SLC22A2, SLC22A25, SLC22A15, SLC22A9, SLC22A4, SLC22A5, SLC22A3, SLC22A16, SLC22A8, SVOPL, SLC22A31, SLC22A13, SLC22A14, SLC22A10 |
| Tissue | brain, occipital.lobe |
| Tissue Specificity | Expressed in brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17253959}; Multi-pass membrane protein {ECO:0000269|PubMed:17253959}. Vacuole membrane {ECO:0000269|PubMed:17253959}; Multi-pass membrane protein {ECO:0000269|PubMed:17253959}. Note=Upon LCN2-binding, it is internalized. |
| Mouse PG classification | NA |
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