| Gene Information | |
|---|---|
| Gene Name | SLC1A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Excitatory amino acid transporter 5 (Retinal glutamate transporter) (Solute carrier family 1 member 7) |
| Target Name | excitatory amino acid transporter 5 |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000162383 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O00341 |
| Gene Card | SLC1A7 |
| Uniprot ID | O00341 |
| Pfam | PF00375 |
| In ASD | no |
| Allosteric Prediction | no (-0.049588999) |
| Ortholog in Animals | Alpaca_ SLC1A7 ( ortholog_one2one ) Dog_ SLC1A7 ( ortholog_one2one ) GuineaPig_ SLC1A7 ( ortholog_one2one ) Macaque_ SLC1A7 ( ortholog_one2one ) Mouse_ Slc1a7 ( ortholog_one2one ) Pig_ SLC1A7 ( ortholog_one2one ) Rat_ Slc1a7 ( ortholog_one2one ) |
| Ohnologs | SLC1A3, SLC1A6, SLC1A1 |
| Paralogs | SLC1A4, SLC1A6, SLC1A2, SLC1A1, SLC1A5, SLC1A3 |
| Tissue | NA |
| Tissue Specificity | Expressed primarily in retina. Detectable in liver, heart, muscle and brain. {ECO:0000269|PubMed:9108121}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs375136400 rs1288401 |
| Subcellular location [CC] | Photoreceptor inner segment membrane {ECO:0000250|UniProtKB:Q8JZR4}; Multi-pass membrane protein {ECO:0000255}. Synaptic cell membrane {ECO:0000250|UniProtKB:Q8JZR4}; Multi-pass membrane protein {ECO:0000255}. Note=Located in both cone and rod photoreceptor terminals and in axon terminals of rod bipolar cells. {ECO:0000250|UniProtKB:Q8JZR4}. |
| Mouse PG classification | NA |
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