| Gene Information | |
|---|---|
| Gene Name | SLC1A6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 564 |
| Protein Names | Excitatory amino acid transporter 4 (Sodium-dependent glutamate/aspartate transporter) (Solute carrier family 1 member 6) |
| Target Name | excitatory amino acid transporter 4 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000105143 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P48664 |
| Gene Card | SLC1A6 |
| Uniprot ID | P48664 |
| Pfam | PF00375 |
| In ASD | no |
| Allosteric Prediction | yes (0.514998127) |
| Ortholog in Animals | Alpaca_ SLC1A6 ( ortholog_one2one ) Dog_ SLC1A6 ( ortholog_one2one ) GuineaPig_ SLC1A6 ( ortholog_one2one ) Macaque_ SLC1A6 ( ortholog_one2one ) Mouse_ Slc1a6 ( ortholog_one2one ) Pig_ SLC1A6 ( ortholog_one2one ) Rat_ Slc1a6 ( ortholog_one2one ) Rabbit_ SLC1A6 ( ortholog_one2one ) |
| Ohnologs | SLC1A3, SLC1A1, SLC1A4, SLC1A7 |
| Paralogs | SLC1A4, SLC1A2, SLC1A7, SLC1A1, SLC1A5, SLC1A3 |
| Tissue | testis, cerebellum |
| Tissue Specificity | Brain, mainly in the cerebellum (PubMed:7791878). Expressed densely and selectively in cell bodies of Purkinje cells. {ECO:0000269|PubMed:7791878}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26690923, ECO:0000269|PubMed:7791878}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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