| Gene Information | |
|---|---|
| Gene Name | EPHA6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1036 |
| Protein Names | Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12) |
| Target Name | ephrin type-a receptor 6 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000080224 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UF33 |
| Gene Card | EPHA6 |
| Uniprot ID | Q9UF33 |
| Pfam | PF14575; PF01404; PF07699; PF00041; PF07714; PF00536 |
| In ASD | no |
| Allosteric Prediction | yes (0.379825484) |
| Ortholog in Animals | Alpaca_ EPHA6 ( ortholog_one2one ) Dog_ EPHA6 ( ortholog_one2many ) Macaque_ EPHA6 ( ortholog_one2one ) Mouse_ Epha6 ( ortholog_one2one ) Pig_ EPHA6 ( ortholog_one2one ) Rat_ Epha6 ( ortholog_one2one ) Rabbit_ EPHA6 ( ortholog_one2one ) |
| Ohnologs | EPHA7, EPHB1, EPHB4, EPHA8, EPHA4, EPHB2, EPHA2, EPHA10 |
| Paralogs | EPHA7, NTRK1, EPHB3, ALK, FGFR3, EPHA2, LMTK2, EPHB1, EPHA3, INSR, PDGFRA, EGFR, CSF1R, ERBB3, KIT, NTRK3, DDR1, ERBB4, EPHA8, TEK, MUSK, MERTK, FGFR4, FLT3, EPHB6, FLT1, DDR2, NTRK2, IGF1R, INSRR, EPHB4, PDGFRB, ERBB2, KDR, EPHA5, FGFR2, TYRO3, MST1R, AXL, EPHB2, ROR1, ROR2, ROS1, EPHA10, EPHA4, RET, LTK, FLT4, TIE1, FGFR1, RYK, EPHA1, MET |
| Tissue | testis |
| Tissue Specificity | Expressed in brain and testis. {ECO:0000269|PubMed:14726470}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4857276 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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