| Gene Information | |
|---|---|
| Gene Name | SLC17A8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 589 |
| Protein Names | Vesicular glutamate transporter 3 (VGluT3) (Solute carrier family 17 member 8) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000179520 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8NDX2 |
| Gene Card | SLC17A8 |
| Uniprot ID | Q8NDX2 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | no (-0.612088104) |
| Ortholog in Animals | Alpaca_ SLC17A8 ( ortholog_one2one ) Dog_ SLC17A8 ( ortholog_one2one ) GuineaPig_ SLC17A8 ( ortholog_one2one ) Macaque_ SLC17A8 ( ortholog_one2one ) Mouse_ Slc17a8 ( ortholog_one2one ) Pig_ SLC17A8 ( ortholog_one2one ) Rat_ Slc17a8 ( ortholog_one2one ) Rabbit_ SLC17A8 ( ortholog_one2one ) |
| Ohnologs | SLC17A7, SLC17A6 |
| Paralogs | SLC37A4, SLC17A3, SLC17A6, SLC17A7, SLC17A9, SLC17A2, SLC37A1, SLC17A1, SLC37A3, SLC17A5, SLC37A2, SLC17A4 |
| Tissue | NA |
| Tissue Specificity | Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus. {ECO:0000269|PubMed:12151341}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs45610843 rs121918339 rs11568530 rs11568543 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q7TSF2}. Cell membrane {ECO:0000305|PubMed:33440152}; Multi-pass membrane protein {ECO:0000305}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q7TSF2}. |
| Mouse PG classification | NA |
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