| Gene Information | |
|---|---|
| Gene Name | KIAA0705 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1455 |
| Protein Names | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Atrophin-1-interacting protein A) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86UL8 |
| Gene Card | MAGI2 |
| Uniprot ID | Q86UL8 |
| Pfam | PF00625; PF00595; PF00397 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in brain. {ECO:0000269|PubMed:9647693}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UEP (NMR - ) 1UEQ (NMR - ) 1UEW (NMR - ) 1UJV (NMR - ) 1WFV (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Late endosome {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9WVQ1}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9WVQ1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q9WVQ1}. Photoreceptor inner segment {ECO:0000250|UniProtKB:Q9WVQ1}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q9WVQ1}. Note=Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Membrane-associated in synaptosomes (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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