| Gene Information | |
|---|---|
| Gene Name | SLC10A4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Sodium/bile acid cotransporter 4 (Na(+)/bile acid cotransporter 4) (Solute carrier family 10 member 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000145248 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96EP9 |
| Gene Card | SLC10A4 |
| Uniprot ID | Q96EP9 |
| Pfam | PF01758 |
| In ASD | no |
| Allosteric Prediction | no (-1.049029903) |
| Ortholog in Animals | Alpaca_ SLC10A4 ( ortholog_one2one ) Dog_ SLC10A4 ( ortholog_one2one ) GuineaPig_ SLC10A4 ( ortholog_one2one ) Macaque_ SLC10A4 ( ortholog_one2one ) Mouse_ Slc10a4-ps ( ortholog_one2many ) Mouse_ Slc10a4 ( ortholog_one2many ) Pig_ SLC10A4 ( ortholog_one2one ) Rat_ Slc10a4 ( ortholog_one2one ) Rabbit_ SLC10A4 ( ortholog_one2one ) |
| Ohnologs | SLC10A2, SLC10A3 |
| Paralogs | SLC10A1, SLC10A6, SLC10A2, SLC10A3, SLC10A5 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain and small intestine, and moderately expressed in colon, heart, prostate, and testis. Very low levels were detected in kidney, liver, ovary, placenta, spleen, and thymus. {ECO:0000269|PubMed:18355966}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23589386}; Multi-pass membrane protein {ECO:0000269|PubMed:23589386}. |
| Mouse PG classification | NA |
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