| Gene Information | |
|---|---|
| Gene Name | SLC12A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1083 |
| Protein Names | Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) |
| Target Name | solute carrier family 12 member 7 |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000113504 ) 3 ( ENSG00000276482 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9Y666 |
| Gene Card | SLC12A7 |
| Uniprot ID | Q9Y666 |
| Pfam | PF00324; PF03522 |
| In ASD | no |
| Allosteric Prediction | yes (0.604018421) |
| Ortholog in Animals | Alpaca_ SLC12A7 ( ortholog_one2one ) Dog_ SLC12A7 ( ortholog_one2one ) GuineaPig_ SLC12A7 ( ortholog_one2one ) Macaque_ SLC12A7 ( ortholog_one2one ) Mouse_ Slc12a7 ( ortholog_one2one ) Pig_ SLC12A7 ( ortholog_one2one ) Rat_ Slc12a7 ( ortholog_one2one ) |
| Ohnologs | SLC12A4, SLC12A5, SLC12A6 |
| Paralogs | SLC12A2, SLC12A8, SLC12A1, SLC12A4, SLC12A3, SLC12A5, SLC12A6, SLC12A9 |
| Tissue | NA |
| Tissue Specificity | Detected in muscle, brain, lung, heart and kidney. {ECO:0000269|PubMed:10347194}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7D99 (EM 2.90A ) |
| DBSNP | rs4526148 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10913127}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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