| Gene Information | |
|---|---|
| Gene Name | SLC13A5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 568 |
| Protein Names | Na(+)/citrate cotransporter (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter) (Solute carrier family 13 member 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000141485 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q86YT5 |
| Gene Card | SLC13A5 |
| Uniprot ID | Q86YT5 |
| Pfam | PF00939 |
| In ASD | yes |
| Allosteric Prediction | no (-0.164532534) |
| Ortholog in Animals | Alpaca_ SLC13A5 ( ortholog_one2one ) Dog_ SLC13A5 ( ortholog_one2one ) GuineaPig_ SLC13A5 ( ortholog_one2one ) Macaque_ SLC13A5 ( ortholog_one2one ) Mouse_ Slc13a5 ( ortholog_one2one ) Pig_ SLC13A5 ( ortholog_one2one ) Rat_ Slc13a5 ( ortholog_one2one ) Rabbit_ SLC13A5 ( ortholog_one2one ) |
| Ohnologs | SLC13A3, SLC13A2, SLC13A1, SLC13A4 |
| Paralogs | SLC13A2, SLC13A4, SLC13A1, SLC13A3, OCA2 |
| Tissue | liver, parotid.gland |
| Tissue Specificity | Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis. {ECO:0000269|PubMed:12445824}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 7JSJ (EM 3.12A ) 7JSK (EM 3.04A ) |
| DBSNP | rs761917087 rs150024888 rs144332569 rs587777577 rs142262032 rs150738356 rs548065551 rs148049520 rs587777578 rs863225448 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26384929, ECO:0000269|PubMed:30054523}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | LPG |
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