| Gene Information | |
|---|---|
| Gene Name | SLC15A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 708 |
| Protein Names | Solute carrier family 15 member 1 (Intestinal H(+)/peptide cotransporter) (Oligopeptide transporter, small intestine isoform) (Peptide transporter 1) |
| Target Name | solute carrier family 15 member 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000088386 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P46059 |
| Gene Card | SLC15A1 |
| Uniprot ID | P46059 |
| Pfam | PF00854 |
| In ASD | no |
| Allosteric Prediction | yes (0.681840578) |
| Ortholog in Animals | Alpaca_ SLC15A1 ( ortholog_one2one ) Dog_ SLC15A1 ( ortholog_one2one ) GuineaPig_ SLC15A1 ( ortholog_one2one ) Macaque_ SLC15A1 ( ortholog_one2one ) Mouse_ Slc15a1 ( ortholog_one2one ) Pig_ SLC15A1 ( ortholog_one2one ) Rat_ Slc15a1 ( ortholog_one2one ) Rabbit_ SLC15A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC15A4, SLC15A5, SLC15A3, SLC15A2 |
| Tissue | duodenum, small.intestine, gall.bladder, kidney, pancreas, zone.of.skin, small.intestine.Peyers.patch |
| Tissue Specificity | Expressed in small intestine. {ECO:0000269|PubMed:28408210}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PMW (EM 4.10A ) 7PMX (EM 3.50A ) 7PN1 (EM 3.90A ) |
| DBSNP | rs8187818 rs8187817 rs2297322 rs8187821 rs8187820 rs4646227 rs2274828 rs8187838 rs2274827 rs8187830 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:Q9JIP7}; Multi-pass membrane protein {ECO:0000255}. Apical cell membrane {ECO:0000269|PubMed:28408210}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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