| Gene Information | |
|---|---|
| Gene Name | SLC10A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 340 |
| Protein Names | Sodium/bile acid cotransporter 7 (Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000120519 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q0GE19 |
| Gene Card | SLC10A7 |
| Uniprot ID | Q0GE19 |
| Pfam | PF13593 |
| In ASD | no |
| Allosteric Prediction | no (-1.193238652) |
| Ortholog in Animals | Alpaca_ SLC10A7 ( ortholog_one2one ) Dog_ SLC10A7 ( ortholog_one2one ) GuineaPig_ SLC10A7 ( ortholog_one2one ) Macaque_ SLC10A7 ( ortholog_one2one ) Mouse_ Slc10a7 ( ortholog_one2one ) Pig_ SLC10A7 ( ortholog_one2one ) Rat_ Slc10a7 ( ortholog_one2one ) Rabbit_ SLC10A7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed (PubMed:15932064, PubMed:17628207). Expressed at high levels in liver and at lower levels in prostate, placenta, kidney, heart, lung, thymus and spleen (PubMed:15932064, PubMed:17628207). Strongly expressed in testis and also detected in brain, ovary, colon and small intestine (PubMed:17628207). Weakly expressed in testis and not detected in brain, ovary, colon or small intestine (PubMed:15932064). Isoform 1: Expressed in liver, testis and placenta (PubMed:17628207). Isoform 4: Expressed in liver, testis and placenta (PubMed:17628207). {ECO:0000269|PubMed:15932064, ECO:0000269|PubMed:17628207}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs1560980659 rs1560973571 rs1560973467 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17628207, ECO:0000269|PubMed:30082715}; Multi-pass membrane protein {ECO:0000305|PubMed:17628207}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:17628207}; Multi-pass membrane protein {ECO:0000305|PubMed:17628207}. Golgi apparatus membrane {ECO:0000269|PubMed:29878199}. |
| Mouse PG classification | NA |
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