| Gene Information | |
|---|---|
| Gene Name | PCNT |
| Organism | Homo sapiens (Human) |
| Gene Length | 3336 |
| Protein Names | Pericentrin (Kendrin) (Pericentrin-B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000160299 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | NA |
| Gene Card | PCNT |
| Uniprot ID | O95613 |
| Pfam | PF10495 |
| In ASD | no |
| Allosteric Prediction | no (-0.286584614) |
| Ortholog in Animals | Alpaca_ PCNT ( ortholog_one2one ) Dog_ PCNT ( ortholog_one2one ) GuineaPig_ PCNT ( ortholog_one2one ) Macaque_ PCNT ( ortholog_one2one ) Mouse_ Pcnt ( ortholog_one2one ) Rat_ Pcnt ( ortholog_one2one ) Rabbit_ PCNT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AKAP9 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested, including placenta, liver, kidney and thymus. {ECO:0000269|PubMed:10823944}. |
| Pharmacological Animal Models | 0.025380(Chimpanzee);0.001000(Mouse);0.001823(Rat);0.016667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2249060 rs2839223 rs2839227 rs6518289 rs7279204 rs35044802 rs143796569 rs6518291 rs35940413 rs34268261 rs34813667 rs2839245 rs35978208 rs1044998 rs34151633 rs35346764 rs2070425 rs35848602 rs7277175 rs371893416 rs2839256 rs8131693 rs2070426 rs743346 rs2073376 rs35147998 rs35881595 rs4818842 rs2073380 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:10823944, ECO:0000269|PubMed:11171385, ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:18955030, ECO:0000269|PubMed:22797915, ECO:0000269|PubMed:27137183}. Note=Centrosomal at all stages of the cell cycle. Remains associated with centrosomes following microtubule depolymerization. Colocalized with DISC1 at the centrosome. |
| Mouse PG classification | NA |
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