| Gene Information | |
|---|---|
| Gene Name | SLA |
| Organism | Homo sapiens (Human) |
| Gene Length | 276 |
| Protein Names | Src-like-adapter (Src-like-adapter protein 1) (SLAP-1) (hSLAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000155926 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q13239 |
| Gene Card | SLA |
| Uniprot ID | Q13239 |
| Pfam | PF00017; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.408563452) |
| Ortholog in Animals | Alpaca_ SLA ( ortholog_one2one ) Dog_ SLA ( ortholog_one2one ) GuineaPig_ SLA ( ortholog_one2one ) Macaque_ SLA ( ortholog_one2one ) Mouse_ Sla ( ortholog_one2one ) Pig_ SLA ( ortholog_one2one ) Rat_ Sla ( ortholog_one2one ) Rabbit_ SLA ( ortholog_one2one ) |
| Ohnologs | SLA2 |
| Paralogs | DAPP1, SH2D5, NCK1, GRAP, GRAPL, GRB2, GRAP2, NCK2, SLA2 |
| Tissue | whole.blood |
| Tissue Specificity | Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9660183}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CUD (NMR - ) |
| DBSNP | rs4486183 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Note=Colocalizes with endosomes. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |