| Gene Information | |
|---|---|
| Gene Name | TOB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 345 |
| Protein Names | Protein Tob1 (Transducer of erbB-2 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000141232 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P50616 |
| Gene Card | TOB1 |
| Uniprot ID | P50616 |
| Pfam | PF07742 |
| In ASD | no |
| Allosteric Prediction | no (-0.500099564) |
| Ortholog in Animals | Alpaca_ TOB1 ( ortholog_one2one ) Dog_ TOB1 ( ortholog_one2one ) GuineaPig_ TOB1 ( ortholog_one2one ) Macaque_ TOB1 ( ortholog_one2one ) Mouse_ Tob1 ( ortholog_one2one ) Rat_ Tob1 ( ortholog_one2one ) Rabbit_ TOB1 ( ortholog_one2one ) |
| Ohnologs | TOB2 |
| Paralogs | TOB2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D5R (X-ray 2.50A ) 2Z15 (X-ray 2.30A ) 5CI8 (X-ray 2.33A ) 5CI9 (X-ray 2.30A ) |
| DBSNP | rs3316 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic. {ECO:0000250}. |
| Mouse PG classification | NA |
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