| Gene Information | |
|---|---|
| Gene Name | WDR16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 620 |
| Protein Names | Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16) (WD40-repeat protein up-regulated in HCC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N1V2 |
| Gene Card | CFAP52 |
| Uniprot ID | Q8N1V2 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in respiratory cells and sperm (at protein level) (PubMed:33139725). Highly expressed in testis (PubMed:15967112). Up-regulated in hepatocellular carcinoma (HCC) (PubMed:15967112). {ECO:0000269|PubMed:15967112, ECO:0000269|PubMed:33139725}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs140921334 rs6503235 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15967112}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A8ILK1}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:33139725}. Note=Located in the proximal region of respiratory cilia. {ECO:0000269|PubMed:33139725}. |
| Mouse PG classification | NA |
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