| Gene Information | |
|---|---|
| Gene Name | DACT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 836 |
| Protein Names | Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165617 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NYF0 |
| Gene Card | DACT1 |
| Uniprot ID | Q9NYF0 |
| Pfam | PF15268 |
| In ASD | no |
| Allosteric Prediction | no (-0.636161898) |
| Ortholog in Animals | Alpaca_ DACT1 ( ortholog_one2one ) Dog_ DACT1 ( ortholog_one2one ) GuineaPig_ DACT1 ( ortholog_one2one ) Macaque_ DACT1 ( ortholog_one2one ) Mouse_ Dact1 ( ortholog_one2one ) Pig_ DACT1 ( ortholog_one2one ) Rat_ Dact1 ( ortholog_one2one ) Rabbit_ DACT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DACT3, DACT2 |
| Tissue | ovary, spleen, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002419(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs778976254 rs34015825 rs17832998 rs17094821 rs1198900887 rs698025 rs1028180302 rs773720154 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Synapse {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. Seems to be nuclear in the absence of Wnt signaling and to translocate to the cytoplasm in its presence. |
| Mouse PG classification | NA |
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