| Gene Information | |
|---|---|
| Gene Name | SKA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 412 |
| Protein Names | Spindle and kinetochore-associated protein 3 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000165480 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IX90 |
| Gene Card | SKA3 |
| Uniprot ID | Q8IX90 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.901239055) |
| Ortholog in Animals | Alpaca_ SKA3 ( ortholog_one2one ) Dog_ SKA3 ( ortholog_one2one ) GuineaPig_ SKA3 ( ortholog_one2one ) Macaque_ SKA3 ( ortholog_one2one ) Mouse_ Ska3 ( ortholog_one2one ) Pig_ SKA3 ( ortholog_one2one ) Rat_ Ska3 ( ortholog_one2one ) Rabbit_ SKA3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | appendix, bone.marrow, colon, dura.mater, testis, tongue |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.058983(Mouse);0.002657(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4AJ5 (X-ray 3.32A ) |
| DBSNP | rs11546983 rs17345690 rs17279819 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19289083, ECO:0000269|PubMed:19360002, ECO:0000269|PubMed:20813266}. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. {ECO:0000269|PubMed:19360002}. |
| Mouse PG classification | NA |
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