| Gene Information | |
|---|---|
| Gene Name | SIX4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 781 |
| Protein Names | Homeobox protein SIX4 (Sine oculis homeobox homolog 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000100625 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UIU6 |
| Gene Card | SIX4 |
| Uniprot ID | Q9UIU6 |
| Pfam | PF00046; PF16878 |
| In ASD | no |
| Allosteric Prediction | no (-0.330415384) |
| Ortholog in Animals | Alpaca_ SIX4 ( ortholog_one2one ) Dog_ SIX4 ( ortholog_one2one ) GuineaPig_ SIX4 ( ortholog_one2one ) Macaque_ SIX4 ( ortholog_one2one ) Mouse_ Six4 ( ortholog_one2one ) Pig_ SIX4 ( ortholog_one2one ) Rat_ Six4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SIX2, ANHX, SIX6, SIX3, SIX1, SIX5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.175650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs750515774 rs3742636 rs1264571513 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q61321}. Cytoplasm {ECO:0000250|UniProtKB:Q61321}. |
| Mouse PG classification | NA |
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