| Gene Information | |
|---|---|
| Gene Name | SIPA1L3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1781 |
| Protein Names | Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105738 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O60292 |
| Gene Card | SIPA1L3 |
| Uniprot ID | O60292 |
| Pfam | PF02145; PF11881 |
| In ASD | no |
| Allosteric Prediction | no (-0.883721151) |
| Ortholog in Animals | Alpaca_ SIPA1L3 ( ortholog_one2one ) Dog_ SIPA1L3 ( ortholog_one2one ) GuineaPig_ SIPA1L3 ( ortholog_one2one ) Macaque_ SIPA1L3 ( ortholog_one2one ) Mouse_ Sipa1l3 ( ortholog_one2one ) Pig_ SIPA1L3 ( ortholog_one2one ) Rat_ Sipa1l3 ( ortholog_one2one ) Rabbit_ SIPA1L3 ( ortholog_one2one ) |
| Ohnologs | SIPA1L2, SIPA1L1, SIPA1 |
| Paralogs | SIPA1L2, SIPA1L1, SIPA1, RAP1GAP2, RAP1GAP, GARNL3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs138476311 rs2304133 rs3745945 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:26231217}. Note=Detected in tricellular junctions. Colocalizes with apical F-actin. {ECO:0000269|PubMed:26231217}. |
| Mouse PG classification | NA |
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