| Gene Information | |
|---|---|
| Gene Name | ELAPOR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1013 |
| Protein Names | Endosome/lysosome-associated apoptosis and autophagy regulator 1 (Estrogen-induced gene 121 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000116299 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6UXG2 |
| Gene Card | ELAPOR1 |
| Uniprot ID | Q6UXG2 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.829502684) |
| Ortholog in Animals | Alpaca_ ELAPOR1 ( ortholog_one2one ) Dog_ ELAPOR1 ( ortholog_one2one ) GuineaPig_ ELAPOR1 ( ortholog_one2one ) Mouse_ Elapor1 ( ortholog_one2one ) Pig_ ELAPOR1 ( ortholog_one2one ) Rat_ Elapor1 ( ortholog_one2one ) Rabbit_ ELAPOR1 ( ortholog_one2one ) |
| Ohnologs | ELAPOR2 |
| Paralogs | ELAPOR2 |
| Tissue | NA |
| Tissue Specificity | Expressed in normal endometrium but overexpressed in endometroid tumors. {ECO:0000269|PubMed:16322283}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs678238 rs659543 rs1052878 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:21072319, ECO:0000269|PubMed:26045166}; Single-pass type I membrane protein {ECO:0000269|PubMed:21072319}. Late endosome membrane {ECO:0000269|PubMed:21072319}; Single-pass type I membrane protein {ECO:0000269|PubMed:21072319}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:21072319}; Single-pass type I membrane protein {ECO:0000269|PubMed:21072319}. Lysosome membrane {ECO:0000269|PubMed:21072319}; Single-pass membrane protein {ECO:0000269|PubMed:21072319}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:26045166}; Single-pass type I membrane protein {ECO:0000269|PubMed:21072319}. |
| Mouse PG classification | NA |
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