| Gene Information | |
|---|---|
| Gene Name | SIAE |
| Organism | Homo sapiens (Human) |
| Gene Length | 523 |
| Protein Names | Sialate O-acetylesterase (EC 3.1.1.53) (H-Lse) (Sialic acid-specific 9-O-acetylesterase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000110013 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9HAT2 |
| Gene Card | SIAE |
| Uniprot ID | Q9HAT2 |
| Pfam | PF03629 |
| In ASD | no |
| Allosteric Prediction | no (-0.715668674) |
| Ortholog in Animals | Alpaca_ SIAE ( ortholog_one2one ) Dog_ SIAE ( ortholog_one2one ) GuineaPig_ SIAE ( ortholog_one2one ) Macaque_ SIAE ( ortholog_one2one ) Mouse_ Siae ( ortholog_one2one ) Pig_ SIAE ( ortholog_one2one ) Rat_ Siae ( ortholog_one2one ) Rabbit_ SIAE ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high expression in the testis, prostate, and colon. {ECO:0000269|PubMed:15292578}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs144571829 rs762824510 rs377634657 rs76655561 rs12282107 rs78778622 rs200739060 rs143070599 rs149466359 rs200862001 rs746914032 rs757586703 rs144510878 rs147649509 rs749579541 rs552372846 rs766047951 rs201877149 rs147161431 rs143668140 rs7941523 rs376857712 |
| Subcellular location [CC] | Lysosome {ECO:0000305}. Secreted. |
| Mouse PG classification | NA |
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