Gene Information
Gene NamePARS2
OrganismHomo sapiens (Human)
Gene Length475
Protein NamesProbable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
Target Nameprobable proline--trna ligase, mitochondrial
Target TypeNA
Gene Age1488 ( ENSG00000162396 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ7L3T8
Gene CardPARS2
Uniprot IDQ7L3T8
PfamPF03129; PF00587
In ASDno
Allosteric Predictionno (-0.869631944)
Ortholog in AnimalsAlpaca_ PARS2 ( ortholog_one2one )
Dog_ PARS2 ( ortholog_one2one )
GuineaPig_ PARS2 ( ortholog_one2one )
Macaque_ PARS2 ( ortholog_one2one )
Mouse_ Pars2 ( ortholog_one2one )
Pig_ PARS2 ( ortholog_one2one )
Rat_ Pars2 ( ortholog_one2one )
Rabbit_ PARS2 ( ortholog_one2one )
OhnologsNA
ParalogsTARS2, TARS3, MRPL39, TARS1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11577368  rs1246773873  rs147227819  rs141760650  rs1557762729  rs2270004  rs730882153  rs35201073 
Subcellular location [CC]Mitochondrion matrix {ECO:0000305}.
Mouse PG classificationNA
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