| Gene Information | |
|---|---|
| Gene Name | SLC17A7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Vesicular glutamate transporter 1 (VGluT1) (Brain-specific Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000104888 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9P2U7 |
| Gene Card | SLC17A7 |
| Uniprot ID | Q9P2U7 |
| Pfam | PF07690 |
| In ASD | yes |
| Allosteric Prediction | yes (0.815866043) |
| Ortholog in Animals | Alpaca_ SLC17A7 ( ortholog_one2one ) Dog_ SLC17A7 ( ortholog_one2one ) GuineaPig_ SLC17A7 ( ortholog_one2one ) Macaque_ SLC17A7 ( ortholog_one2one ) Mouse_ Slc17a7 ( ortholog_one2one ) Pig_ SLC17A7 ( ortholog_one2one ) Rat_ Slc17a7 ( ortholog_one2one ) Rabbit_ SLC17A7 ( ortholog_one2one ) |
| Ohnologs | SLC17A6, SLC17A8 |
| Paralogs | SLC17A8, SLC37A4, SLC17A3, SLC17A6, SLC17A9, SLC17A2, SLC37A1, SLC17A1, SLC37A3, SLC17A5, SLC37A2, SLC17A4 |
| Tissue | brain, cerebral.cortex, amygdala, cerebellar.hemisphere, cerebellum, hippocampus |
| Tissue Specificity | Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe. {ECO:0000269|PubMed:10820226}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17855709 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q3TXX4}. Cell membrane {ECO:0000305|PubMed:10820226}; Multi-pass membrane protein {ECO:0000305}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q3TXX4}. |
| Mouse PG classification | NA |
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