| Gene Information | |
|---|---|
| Gene Name | DOK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 4) (ARTC4) (Dombrock blood group carrier molecule) (Mono(ADP-ribosyl)transferase 4) (NAD(P)(+)--arginine ADP-ribosyltransferase 4) (CD antigen CD297) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000115325 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q93070 |
| Gene Card | ART4 |
| Uniprot ID | Q93070 |
| Pfam | PF01129 |
| In ASD | no |
| Allosteric Prediction | no (-0.391216041) |
| Ortholog in Animals | Alpaca_ DOK1 ( ortholog_one2one ) Dog_ DOK1 ( ortholog_one2one ) GuineaPig_ DOK1 ( ortholog_one2one ) Macaque_ DOK1 ( ortholog_one2one ) Mouse_ Dok1 ( ortholog_one2one ) Pig_ DOK1 ( ortholog_one2one ) Rat_ Dok1 ( ortholog_one2one ) Rabbit_ DOK1 ( ortholog_one2one ) |
| Ohnologs | DOK3, DOK2 |
| Paralogs | DOK6, DOK4, DOK2, FRS3, FRS2, DOK3, DOK5 |
| Tissue | NA |
| Tissue Specificity | Expressed in spleen and T-cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28362797 rs28362798 rs28362799 rs28362800 rs11276 rs3088190 |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor. |
| Mouse PG classification | NA |
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