| Gene Information | |
|---|---|
| Gene Name | QKI |
| Organism | Homo sapiens (Human) |
| Gene Length | 341 |
| Protein Names | KH domain-containing RNA-binding protein QKI (Protein quaking) (Hqk) (HqkI) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000112531 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96PU8 |
| Gene Card | QKI |
| Uniprot ID | Q96PU8 |
| Pfam | PF00013; PF16551; PF16544 |
| In ASD | no |
| Allosteric Prediction | yes (0.15670572) |
| Ortholog in Animals | Alpaca_ QKI ( ortholog_one2one ) Dog_ QKI ( ortholog_one2one ) GuineaPig_ QKI ( ortholog_one2one ) Macaque_ QKI ( ortholog_one2one ) Mouse_ Qki ( ortholog_one2one ) Pig_ QKI ( ortholog_one2one ) Rat_ Qk ( ortholog_one2one ) Rabbit_ QKI ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KHDRBS3, SF1, KHDRBS1, KHDRBS2 |
| Tissue | NA |
| Tissue Specificity | Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients. {ECO:0000269|PubMed:16342280}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.010526(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 4JVH (X-ray 3.50A ) |
| DBSNP | rs1258390251 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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