| Gene Information | |
|---|---|
| Gene Name | SPON2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000159674 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BUD6 |
| Gene Card | SPON2 |
| Uniprot ID | Q9BUD6 |
| Pfam | PF06468; PF19028 |
| In ASD | no |
| Allosteric Prediction | no (-0.229723921) |
| Ortholog in Animals | Alpaca_ SPON2 ( ortholog_one2one ) GuineaPig_ SPON2 ( ortholog_one2one ) Macaque_ SPON2 ( ortholog_one2one ) Mouse_ Spon2 ( ortholog_one2one ) Pig_ SPON2 ( ortholog_one2one ) Rat_ Spon2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | THSD7B, SPON1, THSD7A |
| Tissue | NA |
| Tissue Specificity | Expressed in normal lung tissue but not in lung carcinoma cell lines. {ECO:0000269|PubMed:10512675}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3D34 (X-ray 1.80A ) |
| DBSNP | rs6836335 rs922697 rs11247975 rs2279279 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
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