| Gene Information | |
|---|---|
| Gene Name | SHC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 594 |
| Protein Names | SHC-transforming protein 3 (Neuronal Shc) (N-Shc) (Protein Rai) (SHC-transforming protein C) (Src homology 2 domain-containing-transforming protein C3) (SH2 domain protein C3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000148082 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q92529 |
| Gene Card | SHC3 |
| Uniprot ID | Q92529 |
| Pfam | PF00640; PF00017 |
| In ASD | no |
| Allosteric Prediction | yes (0.122248094) |
| Ortholog in Animals | Alpaca_ SHC3 ( ortholog_one2one ) Dog_ SHC3 ( ortholog_one2one ) GuineaPig_ SHC3 ( ortholog_one2one ) Macaque_ SHC3 ( ortholog_one2one ) Mouse_ Shc3 ( ortholog_one2one ) Pig_ SHC3 ( ortholog_one2one ) Rat_ Shc3 ( ortholog_one2one ) Rabbit_ SHC3 ( ortholog_one2one ) |
| Ohnologs | SHC2, SHC4, SHC1 |
| Paralogs | CEP152, SHC1, SHC4 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord. {ECO:0000269|PubMed:8808684}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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