| Gene Information | |
|---|---|
| Gene Name | DNAJA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 480 |
| Protein Names | DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000103423 ) 3 ( ENSG00000276726 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q96EY1 |
| Gene Card | DNAJA3 |
| Uniprot ID | Q96EY1 |
| Pfam | PF00226; PF01556; PF00684 |
| In ASD | no |
| Allosteric Prediction | yes (0.439720636) |
| Ortholog in Animals | Alpaca_ DNAJA3 ( ortholog_one2one ) Dog_ DNAJA3 ( ortholog_one2one ) GuineaPig_ DNAJA3 ( ortholog_one2one ) Macaque_ DNAJA3 ( ortholog_one2one ) Mouse_ Dnaja3 ( ortholog_one2one ) Pig_ DNAJA3 ( ortholog_one2one ) Rat_ Dnaja3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DNAJA2, DNAJA4, DNAJA1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in heart, liver, lung and skeletal muscles. Also expressed in keratinocytes. {ECO:0000269|PubMed:9683573}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.026667(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2CTT (NMR - ) 2DN9 (NMR - ) 6IWS (NMR - ) |
| DBSNP | rs1139653 |
| Subcellular location [CC] | Mitochondrion matrix. Cytoplasm, cytosol {ECO:0000250}. Postsynaptic cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK. {ECO:0000250}. |
| Mouse PG classification | NA |
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