| Gene Information | |
|---|---|
| Gene Name | SHB |
| Organism | Homo sapiens (Human) |
| Gene Length | 509 |
| Protein Names | SH2 domain-containing adapter protein B |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000107338 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15464 |
| Gene Card | SHB |
| Uniprot ID | Q15464 |
| Pfam | PF00017 |
| In ASD | no |
| Allosteric Prediction | yes (0.160957195) |
| Ortholog in Animals | Alpaca_ SHB ( ortholog_one2one ) Dog_ SHB ( ortholog_one2one ) GuineaPig_ SHB ( ortholog_one2one ) Macaque_ SHB ( ortholog_one2one ) Mouse_ Shb ( ortholog_one2one ) Pig_ SHB ( ortholog_one2one ) Rat_ Shb ( ortholog_one2one ) Rabbit_ SHB ( ortholog_one2one ) |
| Ohnologs | SHD, SHF, SHE |
| Paralogs | SHF, SHE, SHD |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9484780}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation. |
| Mouse PG classification | NA |
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