| Gene Information | |
|---|---|
| Gene Name | SHARP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 412 |
| Protein Names | Class E basic helix-loop-helix protein 40 (bHLHe40) (Class B basic helix-loop-helix protein 2) (bHLHb2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated by retinoic acid gene 13 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O14503 |
| Gene Card | BHLHE40 |
| Uniprot ID | O14503 |
| Pfam | PF07527; PF00010 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in cartilage, spleen, intestine, lung, and to a lesser extent in heart, brain, liver, muscle and stomach. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21829689}. Nucleus {ECO:0000269|PubMed:11278694, ECO:0000269|PubMed:21829689, ECO:0000269|PubMed:28797635}. Note=Predominantly localized in the nucleus (PubMed:11278694). {ECO:0000269|PubMed:11278694}. |
| Mouse PG classification | NA |
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