| Gene Information | |
|---|---|
| Gene Name | SH3PXD4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 339 |
| Protein Names | Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (SH3 and PX domain-containing protein 4) (p40-phox) (p40phox) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15080 |
| Gene Card | NCF4 |
| Uniprot ID | Q15080 |
| Pfam | PF00564; PF00787; PF00018 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expression is restricted to hematopoietic cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1H6H (X-ray 1.70A ) 1OEY (X-ray 2.00A ) 1W6X (X-ray 2.00A ) 1W70 (X-ray 1.46A ) 1Z9Q (NMR - ) 2DYB (X-ray 3.15A ) |
| DBSNP | rs387906808 rs35160112 rs2075939 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:8280052}. Endosome membrane {ECO:0000269|PubMed:11684018}; Peripheral membrane protein {ECO:0000269|PubMed:11684018}; Cytoplasmic side {ECO:0000269|PubMed:11684018}. Membrane {ECO:0000269|PubMed:11684018}; Peripheral membrane protein {ECO:0000269|PubMed:11684018}. |
| Mouse PG classification | NA |
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